William Kuykendall was born 1810 in Missouri (Arkansas). At age sixteen Kuykendall accompanied his father and brothers in patrol of the Old San Antonio Road during the Fredonian Rebellion. After that he participated in protective and retaliatory pursuits of Indians. He participated in the Siege of Béxar in 1835. He also provided both horses and corn to the Army of the Republic of Texas in 1836 and 1838. From July to November 1836 he served as a ranger under Col. Edward Burleson. He also served in the army against Rafael Vásquez in 1842. In the late 1840s Kuykendall settled his family near Mesquite Landing in Refugio County. He died at Hynes Bay on February 27, 1862.
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